Diphenhydramine Impurity 2

Diphenhydramine Impurity 2 - Names and Identifiers

Name	3-(Diphenylmethoxy)-1,2-propanediol
Synonyms	Diphenhydramine USP RC B Diphenhydramine Impurity 2 3-benzhydryloxypropane-1,2-diol 3-(benzyhdryloxy) propane-1,2-diol 3-(Diphenylmethoxy)-propan-1,2-diol 3-(Diphenylmethoxy)-1,2-propanediol 3-(DiphenylMethoxy)-1,2-propanediol 1,2-Propanediol, 3-(diphenylmethoxy)- DiphenhydraMine Related CoMpound [3-(Benzyhdryloxy)propane-1,2-diol]
CAS	19574-66-4

Diphenhydramine Impurity 2 - Physico-chemical Properties

Molecular Formula	C16H18O3
Molar Mass	258.31
Density	1.169±0.06 g/cm3(Predicted)
Melting Point	52-54°C
Boling Point	452.6±40.0 °C(Predicted)
Solubility	Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Appearance	Solid
Color	White to Off-White
pKa	13.58±0.20(Predicted)
Storage Condition	Refrigerator

Diphenhydramine Impurity 2 - Risk and Safety

HS Code

2918992090

Diphenhydramine Impurity 2 - Introduction

3-(Diphenylmethoxy)-1,2-propanediol, also known as diphenylmethoxyppanediol or DPMP, is a chemical substance. The following is a description of some of its properties, uses, methods and safety information:

Nature:
-Appearance: DPMP is a white crystalline solid.
-Solubility: It can be dissolved in common organic solvents, such as ethanol, acetone and ether.
-Melting point: The melting point of DPMP is about 62-65 degrees Celsius.

Use:
- DPMP is often used as an intermediate in organic synthesis to synthesize other compounds.
-It is also used in the synthesis and preparation of certain drugs, such as epinephrine and norepinephrine.

Preparation Method:
-Generally, DPMP can be prepared by the esterification reaction of benzyl alcohol and malonic acid. This reaction requires the use of an acid catalyst, such as sulfuric acid or toluene sulfonic acid.

Safety Information:
- DPMP has low toxicity, but it still needs to be handled in accordance with basic safety procedures.
-Wear appropriate protective equipment such as glasses, gloves and protective clothing when using or coming into contact with DPMP.
-Avoid inhaling DPMP dust or contact with skin and eyes.
-Good ventilation should be maintained in the workplace to avoid accumulation of DPMP.
-In case of misuse or exposure, seek medical help immediately and provide your doctor with information about the DPMP.

Please note that the above information is for reference only. When using and handling DPMP, be sure to refer to specific chemical safety information and operating guidelines to ensure safety and correctness.

Last Update：2024-04-09 15:18:07